1995

Year 15

Prof. David Bates

Professor of Neurology,
University of Newcastle-upon-Tyne, United Kingdom

THEME: THE DIAGNOSIS AND MANAGEMENT OF COMA

The clinician's definition of normal consciousness is that condition of a normal individual when awake, the individual being fully responsive to stimuli and indicating awareness by behaviour and speech. There are two components to consciousness namely, one, the arousal component which keeps the patient awake and depends on the reticular activating system (RAS), and two, the content of consciousness or awareness of self and the environment. This latter component includes sensation, emotion and thought which depend, along with other cognitive functions, on the integrity of the cerebral cortex. Insult to the RAS or diffuse insult to the cerebral hemispheres, or both, can result in coma. Coma may be defined as a state of unrousable unresponsiveness.

The management of coma involves resuscitation measures which must be employed alongside the assessment of the patient. Adequate airway and circulation must be ensured, while the brain must receive sufficient nutrient in the form of glucose, Needless to say, basic physiological parameters must also be monitored closely. When hope of recovery of consciousness becomes slim, medical, legal and ethical questions first must be addressed, before life support systems are finally withdrawn.